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Stay in Santa Cruz Region's best hotels!

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Superb: 9+ Very good: 8+ Good: 7+ Pleasant: 6+
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Chairu Eco Hotel 4 stars

Hotel in Santa Cruz de la Sierra

Chairu Eco Hotel features a shared lounge, terrace, a restaurant and bar in Santa Cruz de la Sierra. This 4-star hotel offers a concierge service and a tour desk. really modern and clean. the shower was incredible too. the staff are friendly and nice too.

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9
Superb
843 reviews
Price from
US$50.16
per night

TRYP by Wyndham Santa Cruz 4 stars

Hotel in Santa Cruz de la Sierra

Situated in Santa Cruz de la Sierra, 1.6 km from Gabriel Rene Moreno Autonomous University, TRYP by Wyndham Santa Cruz features accommodation with an outdoor swimming pool, free private parking, a... Beautiful brand new hotel. Huge rooms, great breakfast ( the lady making omelettes was lovely) nice pool. Spotless

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9
Superb
438 reviews
Price from
US$67.15
per night

YVY CASA HOTEL

Hotel in Samaipata

Located in Samaipata, 10 km from Samaipata Fort, YVY CASA HOTEL provides accommodation with a garden, free private parking and a terrace. Great owners and hosts. We stayed a room with a windows that opened which was helpful for a breeze. There is no air Conditioner or fans so the open window was fantastic for the breeze, birds chirping. It was a wonderful stay and would suggest it to anyone. The breakfast is homemade, delicious and expansive.

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9.2
Superb
266 reviews
Price from
US$42.75
per night

Marriott Santa Cruz de la Sierra Hotel 5 stars

Hotel in Santa Cruz de la Sierra

Marriott Santa Cruz de la Sierra Hotel has an outdoor swimming pool, fitness centre, a shared lounge and terrace in Santa Cruz de la Sierra. the staff was exceptionally well trained, kindly and helpful

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9.1
Superb
312 reviews
Price from
US$118.40
per night

Cosmopolitano Hotel Boutique 5 stars

Hotel in Santa Cruz de la Sierra

Offering an outdoor pool, Cosmopolitano Hotel Boutique is located in the historical centre of Santa Cruz de la Sierra. Guests can enjoy the on-site bar. Small hotel but amazing and cozy place, rooms well organized, great service and breakfast!!

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9.1
Superb
895 reviews
Price from
US$84.59
per night

La Vida es Bella

Hotel in Samaipata

Set in Samaipata, 9 km from Samaipata Fort, La Vida es Bella offers accommodation with a garden, free private parking, a shared lounge and a terrace. Great location. Wonderful service. The best breakfast ever. A perfect place to rest and enjoy Samaipata.

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9.3
Superb
113 reviews
Price from
US$60
per night

El Pueblito Hotel Boutique 4 stars

Hotel in Samaipata

Situated in Samaipata, 11 km from Samaipata Fort, El Pueblito Hotel Boutique features accommodation with an outdoor swimming pool, free private parking, a garden and a shared lounge. El Pueblito is a representation of a small town, each room representing parts if the town with exquisite decoration. You have a carpentry, bank, florist, artist’ house, chapel, etc… the view is magnificent. El Pueblito is a nice quiet place to relax. The food is very good as well. The family that owns and runs the hotel is very attentive and warm. 100% recommended!

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9.5
Exceptional
221 reviews
Price from
US$87
per night

Alfonsina Hotel Boutique 5 stars

Hotel in Santa Cruz de la Sierra

Conveniently located only a 10-minute walk from Ventura Shopping Centre, Alfonsina Hotel Boutique. offers accommodations in Santa Cruz de la Sierra. Very beautiful hotel in Santa Cruz. The room we had was spacious, very comfortable and clean - and nicely decorated with lots of cinema references.The breakfast was delicious too. The hotel is a bit off from the historic center but it is a short ride or a slightly longer walk. We would definitely come back and stay here again!

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9.4
Superb
391 reviews
Price from
US$94.50
per night

Suite 5 Estrellas 5 stars

Hotel in Santa Cruz de la Sierra

Set 2.1 km from Gabriel Rene Moreno Autonomous University, Suite 5 Estrellas offers 5-star accommodation in Santa Cruz de la Sierra and has a garden, a restaurant and a bar.

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9.3
Superb
6 reviews
Price from
US$28
per night

Rústico & Hotel Boutique Las Churapas

Hotel in San José de Chiquitos

Rústico & Hotel Boutique Las Churapas features an outdoor swimming pool, garden, a terrace and bar in San José de Chiquitos. The hotel offers both free WiFi and free private parking. The people running this hotel are simply amazing. Kind, helpful and ready with information on the town. During heavy rain they even took us by car to the city centre. What a amazing welcome for us in Bolivia. Room is also very nice and clean with a good bed and good shower. Pool was a bit cold, but great refresher on hot days. If you want to visit Kaa Iya National Park, this is a great place for your tour to start and end.

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9.2
Superb
87 reviews
Price from
US$42.94
per night

Hotels with extra health and safety measures

Find hotels in Santa Cruz Region with added hygiene measures plus high cleanliness ratings

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Most booked hotels in Santa Cruz Region in the past month

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